A clinical case of Fisher-Evans syndrome

Abstract

SFE is a fairly rare disease. In cases where SFE presents with isolated ITP, and the second cytopenia develops after several months or even years, it is impossible to establish a diagnosis immediately. The described patient developed AIGA and ITP at the same time. It is also necessary to remember the importance of determining the Coombs test during the initial diagnosis of ITP and further during patient follow–up, and in patients with ITP and AIG, the basal level of serum immunoglobulins to detect PID. In all cases of SFE, it is necessary to conduct an additional examination using molecular genetic methods in order to find a possible cause of the development of secondary SFE. After the therapy, there is a positive trend in clinical signs and laboratory test results. Taking into account that the prognosis for immune cytopenia in the framework of SFE is quite unfavorable, long-term combined IST is usually recommended. Thus, the above clinical case demonstrates the positive effect ofthe treatment. Taking into account the literature data on the recurrence of the disease, dynamic monitoring of the patient's condition and laboratory tests is necessary