Protective Effects of vitamins E on Alcohol (Ethanol)-Induced Liver Injury in Mice

Abstract

Ethanol liver illness could be a major wellbeing issue around the world. One perspective of ethanol harmfulness that has gotten expanding consideration in later a long time is the part of free radical species within the etiology of liver injury. Vitamins E are cancer prevention agents that rummage at no cost radicals. Aim: The study of hepatoprotective effects of Vitamins E on the liver damage Methods: The effect of 20mg Vitamin E as food supplement administered for 21 days was studied on hepatic damage induced by ethanol (2.0ml/100g body weight per oral for 21 days, 40% v/v) in male mice. Results:-. the level of serum aspartate transaminase (AST) and serum alanine transaminase (ALT) were greater in the animals nurtured with ethanol ( group 2 ) ; and levels of these transaminases were absolutely lower in group 3 The impact of ethanol was smaller in group three mice . There was unimportant variance between the group 3 mice ( P > 0.05) and control