Anti-tuberculosis Conjugates Based on Polysaccharides

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Published: Dec 20, 2022
Keywords:
polymeric complexes tuberculosis prolongation ethambutol

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Shomurotov Shavkat Abduganievich
Institute of Bioorganic chemistry UzAS, PhD, Department of Chemistry of Polysaccharides
Mamatmusaeva Nilufar Erkinovna
Tashkent Pharmaceutical Institute, PhD
Sagdullaev Bakhodir Takhirovich
Institute of Bioorganic chemistry UzAS, DSc, Department of Chemistry of Polysaccharides
Turaev Abbaskhan Sabirkhanovich
Institute of Bioorganic chemistry UzAS, DSc,akademik

Abstract

The research on the synthesis of polymeric complexes of polygalacturonic acid with anti-TB preparations having antituberculosis activity was conducted. The structures were ascertained and studied the physicochemical properties of polymeric systems. Pharmacotoxicological studies have shown that polymeric complexes are less toxic than their low molecular analogues and Mycobacterium of tuberculosis show high sensitivity to the prepared preparations.

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How to Cite
Shomurotov Shavkat Abduganievich, Mamatmusaeva Nilufar Erkinovna, Sagdullaev Bakhodir Takhirovich, & Turaev Abbaskhan Sabirkhanovich. (2022). Anti-tuberculosis Conjugates Based on Polysaccharides. Eurasian Journal of Physics,Chemistry and Mathematics, 13, 66–71. Retrieved from https://geniusjournals.org/index.php/ejpcm/article/view/2937
Issue
Vol. 13 (2022): EJPCM
Section
Articles